ASCP ASCP Certifications ASCP-MLT Questions & Answers

• Question 361:

  Allergic reactions, bacterial/viral meningitis do not cause the presence of blasts to be noted in the CSF. Leukemia with CNS involvement will show immature cells, similarly to the peripheral blood smear.

  

  The image is a stained smear of cerebrospinal fluid. The cells present in this field may indicate what condition?

  A. allergic reaction

  B. bacterial meningitis

  C. leukemia with CNS involvement

  D. viral meningitis

  Correct Answer: C

• Question 362:

  A negative glucose oxidase test and a positive test for reducing sugars in urine indicates the presence of a non-glucose reducing sugar such as galactose, fructose, glyceraldehyde, etc. This is the reason that certain patient populations require additional confirmatory sugar testing on their urine samples.

  A negative glucose oxidase test and a positive test for reducing sugars in urine indicates:

  A. True glycosuria

  B. A false-negative glucose oxidation reaction

  C. The presence of a non-glucose reducing sugar such as galactose

  Correct Answer: C

• Question 363:

  Most researchers believe that the small size and increased density of LDL molecules found in atherogenic dyslipidemia enable the molecules to more easily invade the endothelium and arterial wall of vessels. Why are small dense LDL molecules more atherogenic?

  A. Small dense LDL molecules contain less cholesterol and phospholipid

  B. Small dense LDL molecules increase the concentration of HDL-C in the blood

  C. Small dense LDL molecules increase the concentration of adoponectin and inflammatory cytokines

  D. Small dense LDL molecules have greater mobility in the endothelium and arterial wall

  Correct Answer: D

• Question 364:

  According to the Michaelis-Menton kinetics theory, when a reaction is performed in zero- order kinetics:

  A. The substrate concentration is very low and the reaction rate is dependent on the substrate concentration

  B. The substrate concentration is in excess and the reaction rate is dependent on the enzyme concentration

  C. The enzyme concentration is in excess and the reaction rate is dependent on the substrate concentration

  D. The substrate concentration is equal to Km and the reaction rate is dependent on the enzyme concentration

  Correct Answer: B

• Question 365:

  The federal government has categorized critical biological agents into three groups: A, B, and C. Those agents in category A are highest-priority because they can be easily disseminated or transmitted person-to-person. The federal government has categorized critical biological agents into three groups: A, B, and C. Those agents in category A are highest-priority because they:

  A. Cause moderate morbidity and low mortality.

  B. Could be engineered for mass dissemination at some future date.

  C. Can be easily disseminated or transmitted person-to-person.

  Correct Answer: C

• Question 366:

  A positive spot test shows agglutination of horse erythrocytes when added to patient serum previously absorbed with guinea pig kidney, but not when added to patient serum previously absorbed with beef erythrocyte stroma. The test is generally simple, sensitive, and specific, but false negative are common in young children with mononucleosis.

  The most common rapid slide test (MONOSPOT? for infectious mononucleosis employs:

  A. Horse erythrocytes

  B. Sheep erythrocytes

  C. Intact beef erythrocytes

  D. None of the above

  Correct Answer: A

• Question 367:

  AHG must be added immediately after washing to prevent the possibility of a false negative; a false negative can occur in this situation because previously bound globulins may dissociate from red cells, leaving insufficient antibody coating on the red cells to produce a reaction, or free antibody may directly neutralize antiglobulin reagent.

  Blood bank

  A false-negative reaction while performing the DAT technique may be the result of:

  A. Red cell/AHG tube is over centrifuged

  B. Blood collected in tube containing silicon gel

  C. Saline used for wash stored in glass or metal container

  D. AHG addition delayed for 40 or more minutes

  Correct Answer: D

• Question 368:

  Immunology

  The immunoglobulin molecule is made up of both heavy and light chains - the light chains can be comprised of which of the following:

  A. Alpha or beta

  B. Alpha or lambda

  C. Kappa or beta

  D. Kappa or lambda

  Correct Answer: D

• Question 369:

  Where can one find guidance on the minimum performance standards for clinical laboratories?

  A. Food and Drug Administration (FDA)

  B. Centers for Disease Control and Prevention (CDC)

  C. Clinical Laboratory Improvement Amendments of 1988 (CLIA '88)

  D. National Institutes of Health

  Correct Answer: C

• Question 370:

  Which method remains the "gold standard" for ANA detection?

  A. Radioimmunoassay (RIA)

  B. Lateral Flow Immunoassay

  C. Enzyme Immunoasay (ELISA)

  D. Slide-based immunofluorescent assay (IFA) or Colorzyme

  Correct Answer: D