ASCP ASCP Certifications ASCP-MLT Questions & Answers

• Question 451:

  Vitamin K dependent factors are those that require Vitamin K for their synthesis in the liver. Vitamin K is an important factor to gamma-glutamyl carboxylase which adds a carboxyl group to glutamic acid residues on factors II, VII, IX and X, as well as Protein S, Protein C. In adding the gamma-carboxyl group to glutamate residues on the immature clotting factors Vitamin K is itself oxidized. Deficiency of Vitamin K due to malabsorption, liver disease, etc. may contribute to bleeding disorders because clotting factor maturation depends on Vitamin K.

  Which of these coagulation factors are referred to as "vitamin-K dependent?"

  A. I, V, VIII, XIII

  B. II, V, IX, XII

  C. II, VII, IX, X

  D. XI, XII, Fletcher, Fitzgerald

  Correct Answer: C

• Question 452:

  This patient is most likely suffering from sickle cell anemia. This cell, which is sickle- shaped, is indicative of the presence of hemoglobin S. Polychromasia is also commonly observed in sickle cell anemia.

  After experiencing crippling pain in her chest, Elizabeth's mother rushes her to the Emergency Room. After a complete blood count and differential are ordered, the hematology technologist views many peripheral cells similar in appearance to those found in the image below. Which condition is most likely present?

  A. beta thalassemia

  B. myocardial infarction

  C. sickle cell anemia

  D. hemoglobin c disease

  Correct Answer: C

• Question 453:

  Rapid vascular constriction, not dilation, immediately occurs when there is vascular injury in order to constrict the amount of blood that escapes the vessels; ultimately preventing massive loss of blood.

  Primary hemostatic processes resulting from vascular damage include all of the following EXCEPT:

  A. collagen activates glycoprotein IIb/IIIa during platelet activation

  B. von Willebrand factor mediates platelet adhesion

  C. platelet granule release and fibrinogen mediate platelet aggregation

  D. rapid and immediate vascular dilation occurs

  E. b and c

  Correct Answer: D

• Question 454:

  Antidiuretic hormone, or ADH, has the important role of conserving body water by reducing the loss of water in urine by changing the water permeability of the distal tubule and collecting duct. An increase in ADH causes a concentrated urine since the water is retained and absorbed through the permeable membrane. An decrease in ADH causes the collecting ducts to retain very little water, instead it is excreted as urine.

  Chemistry

  Which of the following action describes the MAJOR property of antidiuretic hormone?

  A. acts on proximal tubules.

  B. changes distal tubule water permeability

  C. Acts on Na/K/(H') pump

  D. cannot be affected by diuretics

  E. controls thirst

  Correct Answer: B

• Question 455:

  Gram positive organisms resist decolorization by ethyl alcohol. The large crystal violet- iodine complex is not able to penetrate the peptidoglycan layer, and is trapped within the cell in gram-positive organisms. Conversely, the outer membrane of gram-negative organisms is degraded and the thinner peptidoglycan layer of gram-negative cells is unable to retain the crystal violet-iodine complex and the color is lost.

  What is the purpose of using ethyl alcohol or acetone in the gram stain procedure:

  A. Fix all gram positive organisms

  B. Decolorize all gram positive organisms

  C. Decolorize all gram negative organisms

  D. Fix all gram negative organisms

  Correct Answer: C

• Question 456:

  The primary mechanism responsible for glomerular filtration is:

  A. Osmotic gradient

  B. Concentration of blood components

  C. Rate of blood flow through the kidneys

  D. Hydrostatic differential in glomerular tufts

  Correct Answer: D

• Question 457:

  Hemoglobin F has a high affinity for oxygen. When Hb F is elevated, cells containing Hb S are more oxygenated and do not sickle as readily as they would if Hb F were not present or present in small quantities. Which hemoglobin, when elevated, acts as a protection against sickling in patients with HbS?

  A. Hemoglobin A2

  B. Hemoglobin C

  C. Hemoglobin F

  D. Hemoglobin G

  Correct Answer: B

• Question 458:

  Pink or Red stopper tubes can be used for Blood Bank! Question options:

  A. True

  B. False

  Correct Answer: A

• Question 459:

  HCG levels rise rapidly during the first trimester, then the levels start to decline around week 16. The hCG levels slowly decrease and can level off during the remainder of the pregnancy. The following BEST describes serum hCG levels during pregnancy:

  A. Rise in levels throughout pregnancy

  B. Highest levels found at end of pregnancy

  C. Rapid rise in levels during first trimester; slow decline and possible level-off throughout remainder of pregnancy

  D. Slow rise in levels during first trimester; rapid rise during second trimester; slow decline during the third trimester

  Correct Answer: C

• Question 460:

  Myoglobin rises typically within 2-4 hours after a myocardial infarction and stay elevated for days, with a peak at the 6-9-hour mark post-MI. After myoglobin, troponin is the next fastest to rise afer a mycardial infarction and can rise within 3-4

  hours with a peak around 12 hours post-MI. LD (8-12 hours, 24-48 hour peak) and CK (4-6 hours with peak at 24-36 hours) will also rise after MI, but are not as fast to rise as myoglobin and troponin.

  Chemistry

  A patient is admitted to the hospital with acute chest pain, but which of the following cardiac markers will be elevated FIRST if the patient had an MI?

  A. LD

  B. CK

  C. Myoglobin

  D. Troponin

  Correct Answer: C