One of the following may cause a laboratory acquired infection (LAI):
A. Needlestick exposure
B. Cut on the employee's hand that is not covered
C. Applying chapstick in the laboratory
D. All of the above
The Western Blot Assay is used as a confirmatory test for which of the following:
A. HBsAg
B. CMV Antibody
C. Anti-HCV
D. Anti-HIV-1
Which one of the following conditions is NOT associated with hereditary spherocytosis?
A. Increased osmotic fragility
B. An MCHC greater than 37%
C. Intravascular hemolysis
D. Extravascular hemolysis
Public health guidelines recommend that manipulation of samples for influenza testing be done inside a safety cabinet. Safety goggles could be worn if the specimen or procedure may be prone to splashes or sprays of infectious material. Utility gloves are not necessary.
Public health guidelines recommend that laboratory specimens for influenza testing must be manipulated using which of the following safety precautions?
A. Safety goggles
B. Safety cabinet
C. Utility gloves
D. None of the above
Intravascular hemolysis is typically associated with increased levels of serum (plasma) LDH and bilirubin, and an increased number of reticulocytes. Serum LDH is found in higher levels during intravascular hemolysis due to fact that high levels of LDH are normally found within the red cells, but is now being spilled into the bloodstream via red cell lysis. Bilirubin is a breakdown product of hemoglobin, which has also been spilled into the bloodstream from broken red blood cells via hemolysis. Reticulocytosis is a reflection of the release of an increased number of immature red blood cells from the marrow to account for the red blood cells that are lost through hemolysis. This is a normal response. Failure to show an increased reticulocyte count with hemolytic episodes or hemorrhage would indicate an ineffective erythropoiesis (possible bone marrow function problem).
Which of these blood levels will increase during intravascular hemolysis?
A. Serum (plasma) LDH
B. Serum (plasma) bilirubin
C. Reticulocytes
D. All of the above
E. None of the above
A young man is experiencing difficult breathing after fainting. The physician orders a blood gas analysis which shows the following results: pH = 7.25 pCO2 = 62 mmHg pO2 = 70 mmHg HCO3 = 23 mEq/L Which condition is most likely afflicting this patient?
A. metabolic alkalosis
B. metabolic acidosis
C. respiratory alkalosis
D. respiratory acidosis
2(2)2s = reject when 2 consecutive control measurements exceed the same mean plus 2s or the same mean minus 2s control limit.
Violation of this Westgard rule is usually caused by a systematic error.
Laboratory Operations
Which of the following describes the Westgard multirule 2(2)S?
A. Two control data points are within + 2s
B. One control data point falls outside +2s and a second point falls outside -2s
C. Two consecutive data points fall outside +2s or fall outside -2s
D. Two consecutive data points fall outside +2s
E. Synonymous with R4s
The term affinity refers to the strength of attraction between a single antigenic determinant and a corresponding antigen binding site. The term avidity refers to the total strength of the attraction between an antibody and a multivalent antigen. The reaction between an IgM molecule (which has 10 antigen binding sites), and a multivalent antigen is therefore much stronger than that of an IgG antibody (which has only 2 antigen binding sites).
Avidity is best described by which of the following statements:
A. The strength with which red cells agglutinate
B. The strength with which multivalent antigens and antibodies bind
C. The strength with which univalent antigens and antibodies bind
D. The speed with which an antigen-antibody reaction occurs
Vitamin K is needed to produce certain coagulation factors, in particular factors II, VII, IX, and X. Deficiencies in these factors can lead to increased clotting times and can cause hemorrhagic disease. A deficiency in which of these vitamins leads to increased clotting time and may result in hemorrhagic disease?
A. Riboflavin
B. Pyridoxine
C. Tocopherols
D. Vitamin K
E. Vitamin C
Delayed hemolytic transfusion reactions (DHTR) usually occur within which time period?
A. 5 hours after transfusion
B. 24 hours after transfusion
C. 3-10 days after transfusion
D. one year after transfusion Answer:
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