ASCP ASCP Certifications ASCP-MLT Questions & Answers

• Question 271:

  Allergen-specific IgE, synthesized in response to allergens, becomes fixed to receptors on cellular membranes, especially those of basophils. If these receptor-bound IgE molecules are aggregated on re-exposure to specific allergen, both mast cells and basophils produce mediators that result in the allergic response. IgE-antigen interaction at the cell surface causes degranulation of cells and release of substances including: histamine, SRS-A, platelet activator, a kallikrein, and an eosinophil chemotactic factor. Basophils are the principal cells that bind IgE antibody while their number of receptor sites is proportional to serum IgE levels. Eosinophils are drawn to the site by the basophil chemotaxis mechanism, but are not the main cell which binds the IgE antibody.

  Immunology

  The mediator cells that bind MOST to IgE antibodies are:

  A. Basophils

  B. Eosinophils

  C. Polymorphonuclear neutrophils

  D. Macrophages

  Correct Answer: A

• Question 272:

  Provide the equivalent measurement for 75 milligrams. Question options:

  A. 75,000 micrograms

  B. 750 micrograms

  C. 750,000

  D. 7500 micrograms

  Correct Answer: A

• Question 273:

  MLTs must be provided with free immunization for:

  A. hepatitis C

  B. hepatitis A

  C. HIV

  D. hepatitis B

  Correct Answer: D

• Question 274:

  Bacterial contamination of platelets is most likely because they are stored at room temperature. Bacterial contamination is MOST likely in which of the following blood products?

  A. Red Blood Cells

  B. Red Blood Cells Frozen

  C. Platelets

  D. Fresh Frozen Plasma

  Correct Answer: C

• Question 275:

  The coagulation department tests samples for:

  A. prothrombin times

  B. bacterial growth

  C. electrolytes

  D. complete blood counts

  Correct Answer: A

• Question 276:

  Creatinine clearance tests are utilized to estimate the glomerular function of the kidney. The creatitine clearance calculation is defined as the volume of plasma that is cleared of creatinine by the kidney per unit of time and uses the following

  formula:

  creatinine clearance = Urine creatinine conc x Volume / Plamsa creatinine conc

  Creatinine clearance measurements have a recommended specimen requirement = 24- hour urine collection.

  Which of the following tests would be useful in the assessment of glomerular filtration:

  A. 24 hour urine protein

  B. Creatinine clearance

  C. PSP test

  D. Urea clearance

  Correct Answer: C

• Question 277:

  HLA-DR is a class II MHC.

  HLA-A, HLA-B, and HLA-C are all class I MHC.

  Which of the following antigens is classified as a Major Histocompatibility Complex

  Class II antigen (MHCII)?

  A. HLA-A

  B. HLA-B

  C. HLA-C

  D. HLA-DR

  Correct Answer: D

• Question 278:

  The anticoagulant present in a light-blue stopper tube is:

  A. Ethylenediaminetetraacetic acid (EDTA)

  B. sodium citrate

  C. heparin

  D. potassium oxalate

  Correct Answer: B

• Question 279:

  The characteristic that distinguishes vancomycin-resistant Enterococcus faecium and Enterococcus faecalis from other Enterococcus species is their lack of motility.

  Enterococci are all catalase-negative. Growth on bile esculin agar and in 6.5% salt broth are two characteristics that have commonly been used to identify Enterococcus to the genus level. A positive esculin in combination with a positive PYR

  reaction is another approach to presumptive identification.

  Which one of these characteristics distinguishes vancomycin-resistant Enterococcus faecium and Enterococcus faecalis from other Enterococcus species?

  A. PYR positive reaction

  B. Non-motility

  C. Catalase negative

  D. Growth on bile esculin agar

  Correct Answer: B

• Question 280:

  MCH is the average weight of hemoglobin in the average red blood cell. The value is expressed in picograms (10-12 grams).

  Hematology

  Hemoglobin (g/100ml) x 10 / RBC count (millions/mm3) is the formula for calculating:

  A. MCHC

  B. MCV

  C. MCH

  D. RDW

  Correct Answer: C