ASCP ASCP Certifications ASCP-MLT Questions & Answers

• Question 481:

  Hives and rash usually indicate an allergic reaction. Hematuria is due to a variety of causes. Fever and chills usually indicate a febrile reaction. Positive DAT due to conditions other than sensitization to red cell alloantigens is not uncommon. Therefore a positive DAT in the posttransfusion specimen with a negative DAT in the pretransfusion specimen is more likely to indicate alloimmunization.

  The most definite indication that a patient has been sensitized to a specific red cell antigen is:

  A. Hives and rash

  B. A positive posttransfusion DAT in a patient with a previously negative DAT

  C. A positive posttransfusion DAT in a patient with a previously positive DAT

  D. Hemoglobinuria

  Correct Answer: B

• Question 482:

  No HLA matching is performed for corneal tissue transplants as the cornea occupies a privileged site not usually seen by the immune system. This term has been coined "immune privileged".

  Corneal tissue may be transplanted successfully from one patient to another because:

  A. Anti-corneal antibodies are easily suppressed

  B. Corneal antigens do not activate T cells

  C. The cornea is non-antigenic

  D. The cornea occupies a privileged site not usually seen by the immune system

  E. The cornea has the same DNA in everyone.

  Correct Answer: D

• Question 483:

  Gating sets up boundaries around a subset of data points to segregate those events for analysis.

  Gating the proper cell population is crucial for flow cytometric analysis. The CD marker information presented on the histogram data is only representative of the cells inside the gate.

  When analyzing the raw data of a sample on the flow cytometer, CD marker information on the histograms represents data inside the _____ population.

  A. Gated

  B. Non-gated

  Correct Answer: A

• Question 484:

  A positive RPR test and a negative FTA-ABS test is most likely the result of:

  A. Primary syphilis

  B. Secondary syphilis

  C. Latent syphilis

  D. False positive reaction

  Correct Answer: D

• Question 485:

  In excess triglycerides, the triglycerides reduce the amount of cholesterol in LDL particles producing small dense LDL molecules. Because of size and density, these molecules more easily enter damaged endothelium and vessel walls and are more easily incorporated as plaque is formed.

  Which statement best describes small dense LDL particles that can occur in atherogenic dyslipidemia?

  A. Small dense LDL molecules are less atherogenic than larger, less dense or buoyant LDL particles because they are metabolized faster

  B. Small dense LDL molecules transport more cholesterol and thus are more atherogenic

  C. Small dense LDL molecules are more atherogenic because they can more easily move into the endothelium and vessel wall

  Correct Answer: C

• Question 486:

  Synovial fluid is actually quite viscous and does not have the same consistency as plasma. The reason for its thicker consistency is to provide cushion and reduce friction between the articular cartilage of synovial joints during movement.

  Urinalysis and Other Body Fluids

  All of the statements below about synovial fluid are true EXCEPT:

  A. arthrocentesis is performed as a means to evaluate arthritis and other joint disorders

  B. synovial fluid is present only in movable joints

  C. joint fluid resembles plasma in viscosity

  D. joint fluid has approximately the same glucose as plasma

  Correct Answer: C

• Question 487:

  Blood plasma will contain coagulation proteins, but not in a clotted tube where serum is present. Blood serum contains each of the following substances except:

  A. Water

  B. Sugars

  C. Coagulation proteins

  D. Electrolytes

  Correct Answer: C

• Question 488:

  The tube to the left is a slant of esculin medium, the tube to the right contains heart infusion broth with 6.5% sodium chloride. The bacterial species characteristically producing the positive reactions seen in each of these tubes is most likely:

  A. Staphylococcus aureus

  B. Streptococcus bovis

  C. Enterococcus faecalis

  D. Listeria monocytogenes

  Correct Answer: A

• Question 489:

  There are many causes of CSF lymphocytosis. Lymphocytosis is seen in viral, fungal, and tuberculous infections, although a predominance of neutrophils may be present in the early stages of these infections. Lumbar puncture to obtain CSF samples is often contraindicated in those with a suspected brain abscess.

  CSF lymphocytosis is associated with all of the following except:

  A. Cerebral abscess

  B. Viral meningitis

  C. Chronic fungal meningitis

  D. Chronic tuberculous meningitis

  Correct Answer: A

• Question 490:

  The intended response is Vitamin B12 and folate deficiencies. Each of these conditions lead to a megaloblastic production of the red blood cells in the bone marrow. Since vitamin B12 and folate are needed in order to produce a synchronous development of the nucleus with the cytoplasm in hematologic cells, oval-macrocytosis often occurs if these nutrients are not in adequate supply within the body. This can also affect neutrophils, allowing for the characteristic hypersegmented nucleus.

  The photographic field contains several oval-macrocytes and a hypersegmented neutrophil with greater than 5 nuclear segments. Oval macrocytes are most commonly associated with pernicious anemia and malabsorption syndromes leading to vitamin B12 and folic acid deficiencies.

  Clinical information relating to chronic infection, aplastic anemia, and other hematologic maligancies provide the context for the presence of the oval macrocyte.

  

  Macrocytic erythrocytes and hypersegmented neutrophils are not present in thalassemias or in Pelger-Huet anomaly (hyposegmented neutrophils). Conditions suggested by the macrocytes and the neutrophil in the photograph to the right include which of the following?

  A. Thalassemia

  B. Vitamin B12 deficiency

  C. Pelger-Huet anomaly

  D. Folate deficiency

  Correct Answer: BD